Analogs/Derivatives of Morphine

Heroin

Heroin
diacetylmorphine
Not a natural product
More potent than morphine
It shows a considerably stronger euphoric effect than morphine
Its manufacture is legally prohibited
Penetrates blood barrier faster than morphine (X100)
metabolism: successive deacetylation
intermediate: monoacetylmorphine

heroin.pdb


This web page was updated on March 21, 1997.
By Horacio F. Olivo
http://www.uiowa.edu/~mnpcphar/olivo/morphine/morphine.html