The University of Kansas

41st Annual MIKI Meeting

 

Session IV: Poster Presentations, March 29, 2003

 

1.         Synthesis and Interaction Studies on Therapeutically Active Glycosaminoglycan Oligosaccharides

Fikri Y. Avci, Tasneem F. Islam, Nathalie Karst, Saravanababu Murugesan, Jinzhou Zhan and Robert J. Linhardt*

                        University of Iowa

 

2.         Structural and Kinetic Comparison of Glyphosate Resistant Staphylococcus aureus EPSP Synthase and the Corresponding Mutant of Escherichia coli

            Melanie A. Priestman and Ernst Schönbrunn*

                        University of Kansas

 

3.         Molecular Similarity Derived Universal Descriptors for Property Prediction

            Craig L. Senese, Jane Tseng, Jose S. Duca and A.J. Hopfinger*

                        University of Illinois at Chicago

 

4.         Synthesis and Evaluation of 4,5,6,7-Tetrahydrothieno [3,2-C]pyridine (THTP) Inhibitors of Phenylethanolamine N-Methyltransferase (PNMT)

Mitchell R. Seim, Kevin R. Criscione, Seema Bhat and Gary L. Grunewald*

University of Kansas

 

5.         Microbial Bioconversion of Chalcones

Roberto Carrizo Flores, Monica Sanchez-Gonzalez and John P.N. Rosazza*

                        University of Iowa

 

6.         Catechol Estrogen 4-Hydroxyequilenin is a Substrate and an Inhibitor of Catechol-O-methyltransferase

Yan Li, Jiaqin Yao, Minsun Chang, Huaping Wu, Xiaofeng Yang, Julie E. Goodman, Xuemei Liu, Hong Liu, Andrew D. Mesecar, Richard B. van Breeman, James D. Yager and Judy L. Bolton*

                        University of Illinois at Chicago

 

7.         Protection of Mice from Acetaminophen-Induced Hepatotoxicity by a Sulfhydryl-Protected Prodrug of Glutathione

            J.F. Cohen, D.L. Crankshaw, L.I. Berkeley and H.T. Nagasawa*

                        University of Minnesota

 

8.         A Novel, Highly Efficient Route to Enantiopure, Cyclic and Bicyclic Enaminones:  Application Towards the Total Synthesis of Indolizidine Alkaloid Tyloindicine I

            Brandon J. Turunen and Gunda I. Georg*

            University of Kansas

 

9.         Dereplication of Plant Extracts in Natural Product Drug Discovery

William P. Jones, Hyee-Byung Chai, Norman R. Farnsworth, Geoffrey A. Cordell, Steven M. Swanson and A. Douglas Kinghorn*

                        University of Illinois at Chicago

 

10.       Interactions of Wild Type and Mutant Rat Aryl Sulfotransferase IV (ST1A1) with Chiral Substrates

            Atmaja Saxena, Jonathan J. Sheng and Michael W. Duffel*

                        University of Iowa

 

11.       Molecular Dynamic Simulation of Homology-Based Mu Opioid Receptor in Phospholipid Bilayer

Yan Zhang, Yuk Y. Sham, Ramkumar Rajamani, Jiali Gao and Philip S. Portoghese*

                        University of Minnesota

 

12.       Determination of Gingerols and 6-Shogaol in Ginger Dietary Supplements Using High Performance Liquid Chromatography with Tandem Mass Spectrometry

Yi Tao, Wenkui Li, Yongkai Sun, John F. Fitzloff and Richard B. van Breeman*

University of Illinois at Chicago

 

13.       Design and Synthesis of 3-Trifluoromethyl-7-substituted Tetrahydroisoquinolines as Inhibitors of Phenylethanolamine N-Methyl-transferase (PNMT)

            Jian Lu, Kevin R. Criscione and Gary L. Grunewald*

                        University of Kansas

 

14.       Photoaffinity Labeled Ligands of the PLG Binding Site

            Abigail Fisher and Rodney L. Johnson*

                        University of Minnesota

 

15.       Screening for Ligands that Destabilize a (GAA)6/(TTC)6 Triplex in DNA Using Electrospray Mass Spectrometry

            Xun Cheng, S.V. Santhana Mariappan and Richard B. van Breeman*

                        University of Illinois at Chicago

 

16.       Synthesis of C-Glycoside Analogs

C.C. Chen, S.A. Sikkandar, D. Ress, S. Nacak Baytas, X. Yuan and R.J. Linhardt*

                        University of Iowa

 

17.       Construction and Simulation Modeling of Mycobacterium Tuberculosis Cell Walls

            Xuan Hong and Anton J. Hopfinger*

                        University of Illinois at Chicago

 

18.       Towards the Synthesis of a Novel Pyranosyl Nikkomycin Analog

            Christina S. Stauffer, Pushpal Bhaket and Apurba Dutta*

                        University of Kansas

 

19.       Synthesis of Photoaffinity Labels for the PLG Binding Site

            Bhooma Raghavan and Rodney L. Johnson*

                        University of Minnesota

 

20.       Identification of Phosphorylation Site in Troponin I Using MALDI-TOF Mass Spectrometry

Xiaofeng Yang, Tomoyashi Kobayashi, Huaping Wu, R. John Solaro and Richard B. van Breemen*

University of Illinois at Chicago

 

21.       Structure Analysis of Sulfated Acidic Oligosaccharides

Lianli Chi, Charuwan Thanawiroon, Nur Sibel Gunay, Jin Xie, Stephen Goldman and Robert J. Linhardt*

                        University of Iowa

 

22.       Structure of Pyruvate Kinase with a Novel Allosteric Activator Identified via Computational Docking

            Sasi K. Chilukuri, Bernard D. Santarsiero* and Andrew D. Mesecar*

                        University of Illinois at Chicago

 

23.       Fluorescent Probe for Nucleoside Monophosphate Formation

            Dan Drontle and C.R. Wagner*

                        University of Minnesota

 

24.       Predicting Blood-Brain Barrier Partitioning of Organic Molecules Using Membrane-Interaction QSAR Analysis

            Manisha Iyer, Rama Mishra, Yi Han and A.J. Hopfinger*

                        University of Illinois at Chicago

 

25.       Synthetic Studies Toward the Construction of the cis-Decalin Portion of Superstolides A and B
Zhengmao Hua, Wensheng Yu, Mei Su and Zhendong Jin*

                        University of Iowa

26.       Over-Expression, Purification, and Kinetic Characterization of the Tumor-Specific Isozyme of Pyruvate Kinase M2

            Jill Dombrauckas and Andrew D. Mesecar*

                        University of Illinois at Chicago

 

27.       1,6 Asymmetric Induction in the Lewis Acid-Promoted Reaction of Hydroxyalkyl Azides and Ketones

Christopher E. Katz and Jeffrey Aubé*

University of Kansas

 

28.       4D-QSAR Analysis of a Series of Antifungal P450 Inhibitors and 3D Pharmacophore Comparison as a Function of Alignments

            Jianzhong Liu and Antony Hopfinger*

                        University of Illinois at Chicago

 

29.       Mechanism Studies on the Bioconversion of Isoeugenol to Vanillic Acid and Guaiacol by Nocardia sp. Strain NRRL 5646

            Ramya Seshadri and John P.N. Rosazza*

                        University of Iowa

 

30.       Quantitative Structure Based-Design:  Formalism and Application of Receptor-Dependent (RD) 4D-QSAR Analysis

            Dahua Pan, Yufeng Tseng and  A.J. Hopfinger*

                        University of Illinois at Chicago

 

31.       Synthesis and Evaluation of Potential eIF4E Cap Binding Antagonists

Phalguni Ghosh, Chunkyung Park, Peter Bitterman, Vitaly Polunovsky and Carston R. Wagner*

                        University of Minnesota

 

32.       Total Synthesis of Mycothiol;  The Major Molecular Weight Thiol in Actinomycetes Including Nocardia Species

            Sungwon Lee and John P.N. Rosazza*

                        University of Iowa

 

33.       Structural Basis for Potent Inhibition of Cox-1 and Cox-2 by Resveratrol-A Natural Product in Wine

Barbara Calamini, Bernie Santarsiero, Kiira Ratia, Michael Malkowski, John Pezzuto and Andrew Mesecar*

                        University of Illinois at Chicago

 

34.       Synthesis and Biological Activity of SNC-80 Analogs at Various Opioid Receptors

            Brian Kane, Thomas Metzger and David M. Ferguson*

                        University of Minnesota

 

35.       Potential Cancer Chemopreventive Agents from Aglaia ponapensis

Alison D. Pawlus, Juliana K. Choi, Young Hwa Kang, Norman R. Farnsworth, John M. Pezzuto, Rajendra G. Mehta and A. Douglas Kinghorn*

                        University of Illinois at Chicago

 

36.       Multiple Parallel Syntheses of Monocyclic Quinolone Derivatives

            Jane Buus Laursen, Srinivas Pusuluri and Lester A. Mitscher*

                        University of Kansas

 

37.       Calyptranthes pallens:  A Potential Anticancer Lead Selected Through Plot-Based Collection

Tatiana Lobo-Echeverri, Hee-Byung Chai, Geoffrey A. Cordell, John M. Pezzuto, Steven M. Swanson, D. Doel Soejarto* and A. Douglas Kinghorn*

                        University of Illinois at Chicago

 

38.       Synthesis and Conformational Analysis of O6-Pyridyloxobutylguanine Adduct

John R. Goodell, Mahadevan Seetharaman, Natalia Tretyakova, and David M. Ferguson*

                        University of Minnesota

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